• Users Online: 288
  • Home
  • Print this page
  • Email this page
Home Current issue Archives Ahead of print Search Subscribe Instructions Submit article About us Editorial board Contacts Login 
ORIGINAL ARTICLE
Year : 2013  |  Volume : 34  |  Issue : 3  |  Page : 172-176

Efficacy of repetitive transcranial magnetic stimulation in drug-resistant schizophrenics


Neuropsychiatry Department, Faculty of Medicine, Tanta University, Tanta, Egypt

Correspondence Address:
Amr A. Haiba
Neuropsychiatry Department, Faculty of Medicine, Tanta University, Tanta
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.7123/01.EJP.0000430562.53621.de

Rights and Permissions

Background Despite the advances in pharmacological treatment of schizophrenia, the results are unsatisfactory. Therefore, the search for new antipsychotic drugs and the development of novel treatments for schizophrenia are critical. Transcranial magnetic stimulation is one of the tools that may help schizophrenic patients. Aim of the study To evaluate the efficacy of repetitive transcranial magnetic stimulation (r-TMS) in the treatment of drug-resistant schizophrenic patients. Patients and methods This study included 40 drug-resistant schizophrenic patients. In a random, doubleblind placebo-controlled study, 30 patients were treated by 15 r-TMS sessions to both the left dorsolateral prefrontal cortex and the left temporoparietal cortex for 3 weeks. Ten patients were randomly subjected to sham stimulation (placebo group). Before and after the treatment sessions, all patients were assessed using the Positive and Negative Syndrome Scale, the Calgary Depression Scale for Schizophrenia, and cognitive tests. Results r-TMS could significantly improve only the negative symptoms. The positive symptoms, general psychopathology, and cognitive functions did not show any significant changes. The sham (placebo group) did not show any significant changes in schizophrenic symptoms and cognitive functions. Conclusion r-TMS can be a useful add-on treatment that helps to improve negative schizophrenic symptoms in drug-resistant patients.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1059    
    Printed35    
    Emailed0    
    PDF Downloaded94    
    Comments [Add]    

Recommend this journal